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ARI1A rabbit pAb

簡要描述：SourceRabbitApplicationsIHCReactivityHuman

  • 產(chǎn)品型號(hào)：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2024-05-16
  • 訪  問  量：66

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詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    IHC

  • Reactivity

    Human,Mouse

  • Dilution

    IHC 1:50-300

  • Storage

    -20°C/1 year

  • Specificity

    ARI1A Polyclonal Antibody detects endogenous levels of protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from human protein . at AA range: 1270-1350

  • Uniprot No

    O14497

  • Form

    Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    AT-rich interaction domain 1A(ARID1A) Homo sapiens This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through eit

  • Other

    ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1, AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (B120) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (hOSA1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1) (hELD)

  • Concentration

    1 mg/ml

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