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14-3-3 σ rabbit pAb

簡要描述：SourceRabbitApplicationsWB,IHC,ELISAReactivityHuman,MouseDilutionIHC:100-300

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2024-05-16
  • 訪  問  量：73

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詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB,IHC,ELISA

  • Reactivity

    Human,Mouse

  • Dilution

    IHC: 100-300.WB: 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    14-3-3 σ Polyclonal Antibody detects endogenous levels of 14-3-3 σ protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human SFN. AA range:41-90

  • Uniprot No

    P31947

  • Alternative names

    SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.,function:p53-regulated inhibitor of G2/M progression.,similarity:Belongs to the 14-3-3 family.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN.,tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.,

  • Other

    SFN, 14-3-3 protein sigma

  • Mol.Wt (Da)

    27774

  • Concentration

    1 mg/ml

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