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4E-BP1 rabbit pAb

簡要描述：SourceRabbitApplicationsWB,IHC,ELISAReactivityHuman,Mouse,RatDilutionWB:1:500-1:2000

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2024-05-16
  • 訪  問  量：66

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詳細介紹

  • Source

    Rabbit

  • Applications

    WB,IHC,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-4E-BP1 (S64) Polyclonal Antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at S64.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human 4E-BP1 around the phosphorylation site of Ser64. AA range:30-79

  • Uniprot No

    Q13541

  • Alternative names

    EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    eukaryotic translation initiation factor 4E binding protein 1(EIF4EBP1) Homo sapiens This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008],

  • Other

    EIF4EBP1, Eukaryotic translation initiation factor 4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1

  • Mol.Wt (Da)

    12449

  • Concentration

    1 mg/ml

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