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CD16 mouse mAb(Q32)

簡要描述：SourceMouseApplicationsWB

  • 產品型號：
  • 廠商性質：生產廠家
  • 更新時間：2024-05-16
  • 訪  問  量：56

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詳細介紹

  • Source

    Mouse

  • Applications

    WB,IHC,

  • Reactivity

    Human

  • Dilution

    WB: 1:1000 IHC 1:50-300

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous CD16 protein.

  • Source/Purification

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthetic Peptide of CD16

  • Uniprot No

    P08637/O75015

  • Form

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • Clonality

    Monoclonal

  • Isotype

    IgG

  • Background

    Fc fragment of IgG receptor IIIa(FCGR3A) Homo sapiens This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq,

  • Other

    FCGR3A/FCGR3B, Low affinity immunoglobulin gamma Fc region receptor III-A/Low affinity immunoglobulin gamma Fc region receptor III-B

  • Mol.Wt (Da)

    27940

  • Concentration

    1 mg/ml

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