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CD16 rabbit pAb

簡要描述：SourceRabbitApplicationsIHC

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2024-05-16
  • 訪  問  量：64

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詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human

  • Dilution

    IHC 1:50-200, ELISA 1:10000-20000

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous CD16

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthetic peptide from human protein at AA range: 100-150

  • Uniprot No

    P08637/O75015

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    Fc fragment of IgG receptor IIIa(FCGR3A) Homo sapiens This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq,

  • Other

    FCGR3A CD16A FCG3 FCGR3 IGFR3 FCGR3B CD16B FCG3 FCGR3 IGFR3, Low affinity immunoglobulin gamma Fc region receptor III-A/B (CD16a/b antigen) (Fc-gamma RIII-alpha/beta) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)

  • Concentration

    1 mg/ml

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