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CD209 rabbit pAb

簡要描述：SourceRabbitApplicationsWB,ELISAReactivityHuman,Mouse,RatDilutionWB:1:500-1:2000

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2024-05-16
  • 訪  問  量：68

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詳細介紹

  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CD209 Polyclonal Antibody detects endogenous levels of CD209 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from CD209 antigen at AA range: 261-310

  • Uniprot No

    Q9NNX6

  • Alternative names

    CD209; CLEC4L; CD209 antigen; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD209

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    CD209 molecule(CD209) Homo sapiens This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind mlent ligands with high avidity. Variations in the number of 23 amino a

  • Other

    CD209, CD209 antigen

  • Mol.Wt (Da)

    45775

  • Concentration

    1 mg/ml

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