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CD207 rabbit pAb

簡(jiǎn)要描述:SourceRabbitApplicationsWB,ELISAReactivityHumanDilutionWB:1:500-1:2000

  • 產(chǎn)品型號(hào):
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時(shí)間:2024-05-16
  • 訪  問(wèn)  量:59

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詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CD207 Polyclonal Antibody detects endogenous levels of CD207 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from the Internal region of human CD207. AA range:61-110

  • Uniprot No

    Q9UJ71

  • Alternative names

    CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    CD207 molecule(CD207) Homo sapiens The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],

  • Other

    CD207, C-type lectin domain family 4 member K

  • Mol.Wt (Da)

    36725

  • Concentration

    1 mg/ml

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